Southwest Chicken Bake (Creamy Enchilada Baked Chicken)

This Southwest Chicken Bake is an easy chicken recipe perfect for dinner any night of the week. With just a few ingredients and one dish, you can have the most delicious chicken dinner. This creamy, cheesy baked chicken recipe is covered in enchilada sauce for a Tex-Mex inspired meal the whole family will love!

Southwest Chicken Bake covered in enchilada sauce

Southwest Chicken Bake

This southwest chicken bake is a cheesy enchilada inspired dish the whole family will devour! This creamy baked chicken is so tasty and so easy to make.

Baked Chicken is kind of my specialty around here. Some of my most popular recipes are Baked Chicken Tacos, Baked Caesar Chicken, and Bacon Ranch Chicken Bake. You guys love easy chicken recipes for dinner and so do I! So here’s another delicious baked chicken recipe that I know you and your families will really enjoy.

This Southwest Chicken Bake is creamy, cheesy, and inspired by one of my favorite dishes: chicken enchiladas! I love Mexican food and Tex-Mex dishes, so I wanted to create an easy chicken bake inspired by those flavors. Chicken breast, cheese, tomatoes, green chiles, sour cream, and enchilada sauce mix perfectly in one baking dish…and it only takes a little over 30 minutes to make!

Make this easy baked chicken breast recipe for your next weeknight dinner and you’ll have a delicious meal without any hassle!

This Southwest Chicken Bake is a creamy, cheesy Enchilada Baked Chicken recipe that’s easy to make any night of the week!


Enchilada Baked Chicken breast recipe in a baking dish

Chicken breast cooked in enchilada sauce topped with cheese and cilantro

Creamy, Cheesy Enchilada Baked Chicken

Chicken enchiladas are one of my favorite dishes. I just love the mix of chicken, cheese, and tasty enchilada sauce. So I turned that into an easy chicken dinner recipe that you can make for your family in less than an hour. The chicken is cooked in enchilada sauce and topped with tortilla strips, more cheese, and cilantro. This baked chicken breast recipe brings all of those Tex-Mex flavors into one simple dish that tastes absolutely amazing!

Southwest Chicken Bake with Refried Beans

This Southwest Chicken Bake has so much flavor and is beyond delicious. Now that you’ve got the chicken, you need a great side dish to go with it! These homemade refried beans go perfectly with this cheesy baked chicken breast recipe. The refried beans are the ideal taste and texture, and they are so good served alongside this chicken. It’s the best and easiest Tex-Mex inspired meal to make any night of the week.

Recommended Products to make Southwest Baked Chicken Breast recipe

Southwest Baked Chicken Breast with refried beans

A plate of chicken breast and refried beans

How long do you cook chicken breast in the oven at 375°?

This baked chicken breast recipe should be cooked in the oven for 20-30 minutes. Use a meat thermometer to ensure the chicken has reached the proper temperature.

What is a good internal temperature for chicken breast?

Chicken Breast should always be cooked to an internal temperature of 165°F. It’s important to have a meat thermometer in your kitchen to check the internal temperature of meat any time you cook. Check out this post all about internal temperatures to get a free printable Meat Temperature Chart to make sure you cook all of your meat to the right temp!

Click here to check out our full Baked Chicken Guide for more EASY baked chicken recipes!

Southwest Chicken baked in enchilada sauce

This Southwest Chicken Bake is so creamy, cheesy, and delicious! This Enchilada Baked Chicken Breast recipe is such an easy dinner to make for your family and everyone will love it. Enjoy!

Easy Chicken Dinner Recipes FREE E-Book

We have so many amazing and easy chicken recipes on this site. I love creating delicious chicken dinner recipes to share with you guys, and it seems like you love them too! Click here to get my FREE E-book filled with some of the best chicken recipes all in one place. You’ll find more recipes like this one that are super easy to make any night of the week!

See the recipe card below for details on how to make Southwest Enchilada Baked Chicken. Enjoy!

If you like this baked chicken breast recipe, try these other easy chicken recipes too:


3.45 from 38 votes
This Southwest Chicken Bake is so creamy, cheesy, & delicious. This easy Enchiladas Baked Chicken Breast recipe is perfect for dinner any night of the week!
Southwest Baked Chicken
Prep Time
10 mins
Cook Time
30 mins
Total Time
40 mins
This Southwest Chicken Bake is so creamy, cheesy, & delicious. This easy Enchiladas Baked Chicken Breast recipe is perfect for dinner any night of the week!
Course: Main Course
Cuisine: American
Keyword: baked chicken, enchilada chicken, southwest chicken
Servings: 4
Calories: 404 kcal
Author: Becky Hardin
  • 4 skinless boneless chicken breasts
  • kosher salt & black pepper
  • 1 15 ounce can enchilada sauce
  • 1 14.5 ounce can chopped tomatoes with green chilies, drained
  • 8 ounces sour cream
  • 1 cup Mexican blend shredded cheese
  • Fresh cilantro chopped
  • Cojita cheese crumbled
  • Tortilla corn strips or corn chips
  • Homemade Refried Beans optional side dish. Click for recipe.
  1. Heat oven to 375°F and spray an 8x11-inch baking dish with nonstick spray.
  2. Pound the breasts to an even 1” thickness.
  3. Season both sides of the breasts with salt and black pepper.
  4. Place the chicken in the prepared dish.
  5. In a medium bowl, whisk together enchilada sauce, drained tomatoes, and sour cream. Pour the sauce/sour cream mixture over the chicken.
  6. Bake at 375°F for 20-30 or until the internal temperature, of a middle breast, reads 155°F.
  7. Sprinkle breast with the Mexican blend cheese and cook just until cheese is melted and just beginning to bubble.
  8. Remove chicken from the oven and allow to rest 3-4 minutes.
  9. Serving idea: Place a nest of tortilla chips/strips on the plate and place the chicken on top. Drizzle with extra sauce and garnish with chopped cilantro & crumbled Cotija cheese.
  10. Enjoy!

Recipe Video

Nutrition Facts
Southwest Baked Chicken
Amount Per Serving
Calories 404 Calories from Fat 207
% Daily Value*
Total Fat 23g 35%
Saturated Fat 12g 60%
Cholesterol 163mg 54%
Sodium 1272mg 53%
Potassium 573mg 16%
Total Carbohydrates 15g 5%
Dietary Fiber 2g 8%
Sugars 11g
Protein 32g 64%
Vitamin A 27.9%
Vitamin C 14.8%
Calcium 28.9%
Iron 15.6%
* Percent Daily Values are based on a 2000 calorie diet.
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@Becky I love your recipes, some are tough to cook for me. I really appreciate your dedication about cooking, thanks for all your mouth watering recipes.
Brooke Bohrer
Hello Becky! My husband and I just moved into our first home and we are just starting to cook and we have absolutely loved every recipe of yours we've tried!!!! Thank you!
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