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creamy chicken spaghetti on a spoon

Creamy Chicken Spaghetti

Course: Main Course
Cuisine: American, Italian
Prep Time: 15 minutes
Cook Time: 40 minutes
Total Time: 55 minutes
Servings: 8 people
Calories: 506kcal
This Creamy Chicken Spaghetti is a delicious and hearty baked spaghetti casserole. It's so simple to make, perfect for an easy weeknight meal. Made with simple ingredients and with a wonderfully crunchy, cheesy topping, this dish is pure comfort food.
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For the Topping:

  • 2 cups fresh breadcrumbs or crushed crackers
  • 2 tablespoons butter melted
  • ¼ teaspoon dried basil
  • ¼ teaspoon kosher salt
  • ¾ cup shredded cheese blend

For the Casserole:

  • 2 tablespoons olive oil
  • ½ medium yellow onion finely diced
  • 2 cloves garlic minced
  • 32 ounces chicken broth or stock
  • cups water
  • teaspoons kosher salt
  • ½ teaspoon freshly ground black pepper
  • 16 ounces spaghetti, broken into thirds
  • 2 tablespoons chopped fresh basil
  • 10 ounces (1 can) diced Ro-tel style tomatoes
  • 10 ounces (1 can) cream of mushroom soup
  • 3-4 cups cooked chicken rotisserie is fine
  • cup shredded cheese such as Cheddar, Mexican, Gruyere or a blend


  • Adjust oven rack to middle position and set oven to 350°F. Spray a 9x13-inch casserole dish with nonstick cooking spray.
  • Add oil and onion to a large Dutch oven. Set the pan over medium heat and cook, stirring occasionally, until onion is translucent and has softened.
  • Add minced garlic and cook an additional 30 seconds, stirring often.
  • Add chicken broth and deglaze the pan.
  • Add water, salt, pepper, stir and bring to a boil.
  • Add dried spaghetti (broken into thirds) and reduce heat to medium-low, and cook spaghetti to al dente (according to package directions).
  • Add basil, tomatoes, cream of mushroom soup, chicken and 1¼ cups cheese.
  • Bring mixture just to a low boil and remove from the heat.
  • Pour the chicken spaghetti into the prepared casserole and sprinkle the topping mixture evenly over the top.
  • Bake at 350°F for 30-40 minutes or until hot throughout and cheese is melted. If the cheese is browning too quickly, tent with sprayed aluminum foil.
  • Transfer dish to a cooling rack and let rest 5 minutes before serving.
  • Garnish with fresh chopped basil and serve with fresh green salad and toasty bread.
  • Enjoy!


Calories: 506kcal | Carbohydrates: 68g | Protein: 20g | Fat: 17g | Saturated Fat: 7g | Cholesterol: 33mg | Sodium: 1634mg | Potassium: 451mg | Fiber: 4g | Sugar: 5g | Vitamin A: 378IU | Vitamin C: 12mg | Calcium: 244mg | Iron: 3mg