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sweet and sour sliced brisket on a platter

Sweet and Sour Brisket Recipe

Course: Main Course
Cuisine: American
Prep Time: 20 minutes
Cook Time: 3 hours
Reheat before serving: 45 minutes
Total Time: 4 hours 5 minutes
Servings: 10 people
Calories: 613.85kcal
Author: Becky Hardin
This sweet and sour brisket is full of amazing flavor and so perfectly tender. The brisket is slow cooked a day ahead of time so it's ideal as part of a larger meal. A great turkey alternative for the holidays and perfect for feeding a crowd.
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Ingredients

  • 1 flat-cut aka: first-cut (6-7 pound) brisket
  • 1 medium yellow onion peeled and quartered
  • 2 tablespoons ginger paste
  • 6 cloves garlic halved
  • 1 cup ketchup
  • ½ cup dry red wine
  • ½ cup cider vinegar
  • ¼ cup low-sodium soy sauce
  • ¼ cup honey
  • ¼ teaspoon crushed red pepper flakes
  • ¼ cup + 2 tablespoons Dijon mustard
  • 2 teaspoons coarsely ground black pepper
  • ¼ teaspoon ground cloves
  • ¼ teaspoon freshly grated nutmeg
  • cups root beer cola or ginger ale
  • ½ cup olive oil

Instructions

  • Please read through all instructions and notes before starting.
  • Allow brisket to rest at room temperature 30 minutes before cooking.
  • Heat oven to 325°F and spray a very large baking pan with nonstick spray. The pan should be just large enough to hold the brisket.
  • Place all ingredients EXCEPT the brisket, soda and olive oil into a food processor fitted with the steel blade; process until smooth. Pour the mixture into a large bowl and add the soda and oil. Whisk to fully incorporate.
  • Place brisket, fat cap up, into the prepared baking pan and pour the sauce evenly over it.
  • Cover tightly with aluminum foil and bake 3 hours without peeking. Remove brisket from the oven, and very carefully, remove the foil. Turn the brisket over, tightly cover and bake an additional 3-4 hours or until completely tender. It should easily cut with the side of a fork.
  • Transfer the brisket to a cooling rack, fold the foil back and let the brisket cool to touch. Cover with foil and refrigerate overnight in the cooking pan and juice.
  • The next day, 45 minutes before serving, heat oven to 350°F.
  • Transfer the brisket to a cutting board and remove any rendered, solidified fat from the sauce and cut off the fat from the brisket.
  • Heat oven to 350°F
  • Slice the brisket, against the grain, to desired thickness.
  • Place the brisket back in the pan with the sauce, and drizzle the sauce over the brisket.
  • Cover the pan loosely with foil, and heat the brisket in the oven 30-40 minutes or until warmed throughout.
  • Serve warm with extra sauce. (If the sauce is a little thin, transfer it to a small saucepan, bring to a boil and simmer until desired thickness.)
  • Enjoy!

Notes

NOTE: This brisket is best made the day before, allowed to sit in juices in fridge overnight, and then warmed the next day.

Nutrition

Calories: 613.85kcal | Carbohydrates: 20.01g | Protein: 57.57g | Fat: 31.19g | Saturated Fat: 8.58g | Cholesterol: 168.74mg | Sodium: 724.28mg | Potassium: 1030.19mg | Fiber: 0.55g | Sugar: 16.62g | Vitamin A: 137.94IU | Vitamin C: 2.45mg | Calcium: 29.7mg | Iron: 5.72mg